hPSC-Derived Neural Crest: Induction and Axial Patterning

Neural crest cells migrate long distances in the body and generate a wide variety of cell types, including those in the peripheral nervous system and craniofacial skeleton. Learn how efficient neural crest induction from human pluripotent stem cells (hPSCs) requires exposure to a carefully balanced combination of signals that has been deduced and refined from what we know of neural crest development in the embryo. In this webinar, Dr. James Hackland describes the intricacies of neural crest induction in vitro, as well as recent advances in axial patterning of hPSC-derived neural crest to generate the wide variety of neural crest derivatives that exist in the vertebrate body.
Publish Date: March 18, 2020