Anti-Human HLA-DR Antibody, Clone LN3

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR
From: 118 USD

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Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR
From: 118 USD

Overview

The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II antigen encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein composed of one α (36 kDa) and one β (27 kDa) subunit. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T cells.
Subtype:
Primary Antibodies
Target Antigen:
HLA-DR
Alternative Names:
HLA class II histocompatibility antigen, HLA-DR alpha, HLA-DRA, HLA DRA1, HLA DR1B, HLA DR3B, HLA DRB1, HLA DRB3, HLA DRB4, HLA DRB5, HLADR4B, HLADRA1, HLADRB, Major histocompatibility class II, MHC II, MHC class II, MHC class II antigen DRA, MLRW
Reactive Species:
Human; Rhesus
Conjugation:
FITC; PE; Unconjugated; Alexa Fluor 488
Host Species:
Mouse
Cell Type:
B Cells; Dendritic Cells; Monocytes; T Cells; Other; Macrophages
Application:
Flow Cytometry; Immunohistochemistry; Functional Assay
Area of Interest:
HLA; Immunology; Transplantation Research; Infectious Diseases
Clone:
LN3
Gene ID:
3122/3123
Isotype:
IgG2b, kappa

Scientific Resources

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

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Data and Publications

Data

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, followed by an anti-mouse IgG2b antibody, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11 (Catalog #60072), followed by an antimouse IgG2b antibody, PE (solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, FITC (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, FITC (Catalog #60072FI; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, PE (Catalog #60072PE; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488 (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, Alexa Fluor® 488 (Catalog #60072AD; solid line histogram).

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.