Figure 1. Properties of Human Platelet Lysate Cell Culture Supplements for Ex Vivo Cell Expansion

The human platelet lysate (hPL) product recommended for the expansion of cells ex vivo varies depending on the starting cell type, intended application, and experimental compliance required. (1) Fibrinogen has not been depleted, therefore addition of an anticoagulant (e.g. Heparin Solution; Catalog #07980) is required to inhibit coagulation. (2) Fibrinogen has been depleted during manufacturing. Pharmaceutical-grade heparin derived from porcine intestine is used in the manufacturing process and the concentration of heparin in final product is ≤ 2 IU/mL. (3) Fibrinogen has been depleted during manufacturing; heparin is not added during the manufacturing process and addition of anticoagulants is not required for use of this product.