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Anti-SHIP (C-Terminus) Antibody, Polyclonal

Rabbit polyclonal antibody against human, mouse SHIP

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Anti-SHIP (C-Terminus) Antibody, Polyclonal

Rabbit polyclonal antibody against human, mouse SHIP

From: 562 USD
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Rabbit polyclonal antibody against human, mouse SHIP
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Overview

The SH2-containing inositol phosphatase (SHIP, also called SHIP1) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein.
Subtype
Primary Antibodies
Target Antigen
SHIP
Alternative Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; p150Ship; SHIP1; SHIP-1; s-SHIP; SIP-145
Reactive Species
Human, Mouse
Conjugation
Unconjugated
Host Species
Rabbit
Cell Type
Granulocytes and Subsets, Lymphocytes, Myeloid Cells
Species
Human, Mouse
Application
Immunoblotting, Immunoprecipitation
Area of Interest
Immunology
Clone
Not applicable
Gene ID
3635 (human), 16331 (mouse)
Isotype
Not applicable

Data Figures

Western blot analysis of total cell lysates from human TF-1 cells (lane 1), mouse WEHI-231 cells (lane 2) and mouse bone marrow derived mast cells (BMMCs; lane 3) with Anti-SHIP (C-Terminus) Antibody, Polyclonal (1:1000 dilution). SHIP has a predicted molecular mass of 145 kDa.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Anti-SHIP (C-Terminus) Antibody, Polyclonal
Catalog #
60144
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-SHIP (C-Terminus) Antibody, Polyclonal
Catalog #
60144
Lot #
All
Language
English

Resources and Publications

Educational Materials (2)

Reliable Antibodies for Your Research
Brochure
Reliable Antibodies for Your Research
Human Immune Cytokines
Wallchart
Human Immune Cytokines

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Quality Statement:

PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.

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