Investigating Metabolic Disease with Human Pluripotent Stem Cells
The ability of human pluripotent stem cells (hPSCs) to differentiate into the many specialized cell types of the human body holds great promise for the study and treatment of human disease. Genome editing of hPSCs can allow for more accurate modeling of human diseases by introducing disease-specific mutations or correcting genetic aberrations in patient-derived induced pluripotent stem cell lines. Advances in genetic tools, such as clustered regularly interspaced short palindromic repeat (CRISPR) technology, have improved the ease and efficiency of genome editing in hPSCs.
View this webinar presentation by Dr. Chad Cowan, who discussed his research efforts to understand metabolic disease using the CRISPR/Cas system in human pluripotent stem cells to create genetic disease models.
View this webinar presentation by Dr. Chad Cowan, who discussed his research efforts to understand metabolic disease using the CRISPR/Cas system in human pluripotent stem cells to create genetic disease models.
Publish Date:
May 13, 2016
Related Multimedia
-
Genome Editing From Modeling Disease to Novel Therapeutics
Publish Date: June 20, 2014 -
Understanding Pancreatic Development and Diabetes Using Patient-Specific iPS Cells
Publish Date: April 18, 2016 -
Making Lung Cells from Pluripotent Stem Cells: Disease Modeling and Future Therapies
Publish Date: August 12, 2016 -
Modeling Arrhythmias Using hPSC-Derived Cardiomyocytes and Tracking Their Excitability
Publish Date: August 14, 2017 -
Using CRISPR/Cas9 to Model Stem Cell Organization and Dynamics
Publish Date: August 25, 2017
Explore Our Products
-
Matrix for maintenance of human ES and iPS cells in combination with TeSR™ maintenance media -
cGMP, feeder-free maintenance medium for human ES and iPS cells
