Whole Exome Sequencing Reveals Selective Pressures and Dominant Negative Mutations in hPSC Cultures
View this webinar presentation by Prof. Kevin Eggan (Harvard University) and Dr. Florian Merkle (University of Cambridge) to learn more about genetic variations in human pluripotent stem cell (hPSC) cultures revealed by whole exome sequencing of more than 100 of the world’s hES cell lines, and the importance of maintaining high-quality hPSCs for regenerative medicine and other applications.
The research discussed in the webinar is now published in Nature: Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Publish Date:
April 19, 2017
Related Multimedia
-
Genome Editing From Modeling Disease to Novel Therapeutics
Publish Date: June 20, 2014 -
Investigating Metabolic Disease with Human Pluripotent Stem Cells
Publish Date: May 13, 2016 -
Genetic Stability of Human Pluripotent Stem Cells
Publish Date: October 06, 2016 -
Data Quality and Standards for Pluripotent Stem Cells
Publish Date: September 28, 2018
Explore Our Products
-
cGMP, feeder-free maintenance medium for human ES and iPS cells
