SU5416
Overview
CANCER RESEARCH
· Prevents angiogenesis, thereby inhibiting tumor growth, catalysis and vascularization for a variety of cancers (Litz; Fong et al.).
· Inhibits RET-mediated transformation of NIH-3T3 mouse fibroblasts and Ba/F3 mouse pro-B cells (Mologni et al.).
DISEASE MODELING
· Causes pulmonary hypertension in SuHx rat model of pulmonary arterial hypertension, when combined with hypoxia (de Raaf et al.; Mizuno et al.).
IMMUNOLOGY
· Inhibits TGFβ1 activation and delays wound healing in rats (Haroon et al.).
Scientific Resources
Product Documentation
Document Type | Product Name | Catalog # | Lot # | Language |
---|---|---|---|---|
Document Type
Product Information Sheet
|
Product Name
SU5416
|
Catalog # 73442, 73444 |
Lot # All |
Language English |
Document Type
Safety Data Sheet
|
Product Name
SU5416
|
Catalog # 73442, 73444 |
Lot # All |
Language English |
Data and Publications
Publications (5)
Abstract
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Legal Statement:
Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.