Anti-SARS-CoV Nucleoprotein Antibody, Clone 001 (Recombinant)

Rabbit monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) Nucleoprotein (HEK293-expressed recombinant)

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Rabbit monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) Nucleoprotein (HEK293-expressed recombinant)
From: 265 USD

Overview

The Anti-SARS-CoV Nucleoprotein Antibody, Clone 001 (Recombinant) reacts with the nucleoprotein expressed by SARS-associated coronavirus (SARS-CoV) and has shown to cross-react with SARS-CoV-2 (2019-nCoV).

Coronaviruses infect both animal and human hosts and can cause a wide range of potentially fatal symptoms, including upper respiratory tract infections in humans. These viruses are enveloped and contain single-stranded RNA associated with a nucleoprotein. These nucleoproteins are abundantly produced within CoV-infected cells, where their primary function is to package the viral genome into flexible, helical ribonucleoprotein complexes called nucleocapsids. The nucleocapsid binds to genomic RNA and is understood to interact with viral membrane proteins during virion assembly, therefore playing a critical role in ensuring the efficiency of viral transcription, translation, and assembly. In host cells, the nucleocapsid can directly impact normal cell functions and cause cell-cycle deregulation, increased COX-2 production, and inhibition of interferon production.
Subtype:
Primary Antibodies
Target Antigen:
SARS-CoV Nucleoprotein
Alternative Names:
SARS-CoV Nucleocapsid Protein
Conjugation:
Unconjugated
Host Species:
Rabbit
Application:
ELISA; Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting
Area of Interest:
Immunology; Infectious Diseases; Respiratory Research
Clone:
001
Gene ID:
N/A (GenBank: JX163928.1)
Isotype:
IgG

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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.