Anti-SARS-CoV Nucleoprotein Antibody, Clone 001 (Recombinant)

Rabbit monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) Nucleoprotein (HEK293-expressed recombinant)

Anti-SARS-CoV Nucleoprotein Antibody, Clone 001 (Recombinant)

Rabbit monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) Nucleoprotein (HEK293-expressed recombinant)

From: 304 USD
Catalog #
100-0529_C
Rabbit monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) Nucleoprotein (HEK293-expressed recombinant)

Overview

The Anti-SARS-CoV Nucleoprotein Antibody, Clone 001 (Recombinant) reacts with the nucleoprotein expressed by SARS-associated coronavirus (SARS-CoV) and has shown to cross-react with SARS-CoV-2 (2019-nCoV).

Coronaviruses infect both animal and human hosts and can cause a wide range of potentially fatal symptoms, including upper respiratory tract infections in humans. These viruses are enveloped and contain single-stranded RNA associated with a nucleoprotein. These nucleoproteins are abundantly produced within CoV-infected cells, where their primary function is to package the viral genome into flexible, helical ribonucleoprotein complexes called nucleocapsids. The nucleocapsid binds to genomic RNA and is understood to interact with viral membrane proteins during virion assembly, therefore playing a critical role in ensuring the efficiency of viral transcription, translation, and assembly. In host cells, the nucleocapsid can directly impact normal cell functions and cause cell-cycle deregulation, increased COX-2 production, and inhibition of interferon production.
Subtype
Primary Antibodies
Target Antigen
SARS-CoV Nucleoprotein
Alternative Names
SARS-CoV Nucleocapsid Protein
Conjugation
Unconjugated
Host Species
Rabbit
Application
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Area of Interest
Immunology, Infectious Diseases, Respiratory Research
Clone
001
Gene ID
N/A (GenBank: JX163928.1)
Isotype
IgG

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0529, 100-0580
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0529, 100-0580
Lot #
All
Language
English

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