Thank you for your interest in this product.
Please provide us with your contact information and your local representative
will contact you with a customized quote. Where appropriate, they can also assist you with a(n):
Estimated delivery time for your area
Product sample or exclusive offer
The 2.4G2 antibody reacts with a shared epitope of Fc-gamma receptors CD16 (FcRIII) and CD32 (FcRII) in the mouse. CD16 and CD32 are low affinity receptors for the Fc portion of IgG, with CD32 having a higher affinity for IgG aggregates and immune complexes. CD16 and CD32 are expressed on B cells, monocytes, macrophages, NK cells, neutrophils, granulocytes, mast cells, and dendritic cells. The binding of immunoglobulins to Fc receptors is involved in multiple immunological functions, including phagocytosis, cytotoxocity, and the modulation of immune responses. The 2.4G2 antibody blocks the interaction between IgG and CD16 or CD32, and therefore is used as a pre-treatment to minimize non-specific binding of antibodies to FcR-bearing cells in applications such as flow cytometry, cell sorting, and immunofluorescence.
FCGR2, FCGR3, FC Receptor, IGFR2, IGFR3, Ly-17
Dendritic Cells, Granulocytes and Subsets, Macrophages, Monocytes, Myeloid Cells, NK Cells, T Cells, T Cells, Other Subsets
Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD16/CD32 Antibody, Clone 2.4G2, followed by a mouse anti-rat IgG2b
antibody, FITC (filled histogram), or Rat IgG2b, kappa Isotype Control Antibody, Clone RTK4530 (Catalog #60077), followed by a mouse anti-rat IgG2b
antibody, FITC (solid line histogram).
Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD16/CD32 Antibody, Clone 2.4G2, FITC (filled histogram) or Rat IgG2b,
kappa Isotype Control Antibody, Clone RTK4530, FITC (Catalog #60077FI; solid line histogram).
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
Contact STEMCELL Technologies
StemCell Technologies Inc. and affiliates ("STEMCELL Technologies") does not
share your email address with third parties. StemCell Technologies Inc. will use your email address to
confirm your identity and send you newsletters, transaction-related emails, promotional and customer
your email preferences at any time.