L-DOPA

Dopamine precursor

L-DOPA

Dopamine precursor

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Dopamine precursor
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Overview

L-DOPA exhibits analgesic properties and is a precursor of dopamine (Mena et al.; Park et al.; Rekdal et al.). It has also been the gold standard in Parkinson’s disease treatments for over 50 years. It selectively crosses the blood-brain barrier, whereas dopamine cannot (LeWitt). L-DOPA lowers the number of tyrosine hydroxylase-positive neurons in fetal rat midbrain (Mena et al.).

DISEASE MODELING
· Prevents peripheral synthesis of dopamine from levodopa when co-administered with carbidopa and levodopa in rats (Park et al.).
Alternative Names
3,4-Dihydroxyphenylalanine; Levodopa
Area of Interest
Disease Modeling, Neuroscience
CAS Number
59-92-7
Chemical Formula
C₉H₁₁NO₄
Molecular Weight
197.2 g/mol
Purity
≥ 95%

More Information

More Information
Safety Statement

CA WARNING: This product can expose you to Levodopa which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
L-DOPA
Catalog #
100-0890
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
L-DOPA
Catalog #
100-0890
Lot #
All
Language
English

Resources and Publications

Educational Materials (1)