Anti-Mouse CD27 Antibody, Clone LG.3A10

Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27

Anti-Mouse CD27 Antibody, Clone LG.3A10

Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27

From: 171 USD
Catalog #
60160_C
Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27

Overview

The LG.3A10 antibody reacts with CD27, a 45 - 55 kDa member of the tumor necrosis factor receptor superfamily. CD27 is found on peripheral T cells, memory B cells, and NK cells and in mice has been found on most thymocytes, except CD46-CD8- precursors. CD27 and its ligand CD70 are involved in multiple aspects of T cell biology, including the costimulation and expansion of CD4+ and CD8+ T cells and differentiation to memory CD8+ T cells. CD27 interacts with TRAF family members, resulting in enhanced cellular proliferation and the induction of anti-apoptotic proteins. Additionally, CD27 plays important roles in T cell – B cell interactions and the maturation of effector T cells. The expansion of activated B cells and their differentiation to plasma cells is also reported to be enhanced by CD27.
Subtype
Primary Antibodies
Target Antigen
CD27
Alternative Names
LPFS2, S152, T14, TNFRSF7, Tp55
Reactive Species
Human, Mouse, Rat
Conjugation
PE, Unconjugated
Host Species
Hamster
Cell Type
B Cells, NK Cells, Other, T Cells
Application
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation
Area of Interest
Immunology, Infectious Diseases
Clone
LG.3A10
Gene ID
21940/939/500318
Isotype
IgG1, kappa

Data Figures

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (filled histogram), or an Armenian hamster IgG isotype control antibody, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (solid line histogram).

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, PE (filled histogram) or an Armenian hamster IgG isotype control antibody, PE (solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60160
Lot #
All
Language
English
Catalog #
60160PE, 60160PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60160
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60160PE, 60160PE.1
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

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