3-Methyladenine

PI3K/AKT pathway inhibitor

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PI3K/AKT pathway inhibitor
From: 89 USD

Overview

3-Methyladenine has been reported to inhibit autophagy (Seglen & Gordon) by blocking autophagosome formation via the persistent inhibition of class I and transient inhibition of class III phosphoinositide 3-kinase (PI3K; Wu et al.).


METABOLISM
· Inhibits autophagy in isolated rat hepatocytes (Wu et al.).
Alternative Names:
3-MA; NSC 66389
CAS Number:
5142-23-4
Chemical Formula:
C₆H₇N₅
Molecular Weight:
149.2 g/mol
Purity:
≥ 95%
Pathway:
PI3K/AKT
Target:
PI3K

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STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.