3-Methyladenine

PI3K/AKT pathway inhibitor

3-Methyladenine

PI3K/AKT pathway inhibitor

From: 107 USD
Catalog #
74222_C
PI3K/AKT pathway inhibitor

Overview

3-Methyladenine has been reported to inhibit autophagy (Seglen & Gordon) by blocking autophagosome formation via the persistent inhibition of class I and transient inhibition of class III phosphoinositide 3-kinase (PI3K; Wu et al.).


METABOLISM
· Inhibits autophagy in isolated rat hepatocytes (Wu et al.).
Alternative Names
3-MA; NSC 66389
Cell Type
Cancer Cells and Cell Lines
Species
Human, Mouse, Rat, Non-Human Primate, Other
Area of Interest
Autophagy, Cancer, Metabolism
CAS Number
5142-23-4
Chemical Formula
C₆H₇N₅
Molecular Weight
149.2 g/mol
Purity
≥ 95%
Pathway
PI3K/AKT
Target
PI3K

Scientific Resources

Product Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
3-Methyladenine
Catalog #
74222
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
3-Methyladenine
Catalog #
74222
Lot #
All
Language
English

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