3-Methyladenine
PI3K/AKT pathway inhibitor
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3-Methyladenine -
3-Methyladenine -
Label for 3-Methyladenine -
Label for 3-Methyladenine
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Overview
3-Methyladenine has been reported to inhibit autophagy (Seglen & Gordon) by blocking autophagosome formation via the persistent inhibition of class I and transient inhibition of class III phosphoinositide 3-kinase (PI3K; Wu et al.).
METABOLISM
· Inhibits autophagy in isolated rat hepatocytes (Wu et al.).
METABOLISM
· Inhibits autophagy in isolated rat hepatocytes (Wu et al.).
Alternative Names:
3-MA; NSC 66389
CAS Number:
5142-23-4
Chemical Formula:
C₆H₇N₅
Molecular Weight:
149.2 g/mol
Purity:
≥ 95%
Pathway:
PI3K/AKT
Target:
PI3K
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