3-Methyladenine

PI3K/AKT pathway inhibitor
Catalog #
74222_C
PI3K/AKT pathway inhibitor
From: 98 USD

Overview

3-Methyladenine has been reported to inhibit autophagy (Seglen & Gordon) by blocking autophagosome formation via the persistent inhibition of class I and transient inhibition of class III phosphoinositide 3-kinase (PI3K; Wu et al.).


METABOLISM
· Inhibits autophagy in isolated rat hepatocytes (Wu et al.).
Alternative Names
3-MA; NSC 66389
Cell Type
Cancer Cells and Cell Lines
Species
Human, Mouse, Rat, Non-Human Primate, Other
Area of Interest
Autophagy, Cancer, Metabolism
CAS Number
5142-23-4
Chemical Formula
C₆H₇N₅
Molecular Weight
149.2 g/mol
Purity
≥ 95%
Pathway
PI3K/AKT
Target
PI3K

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet
Product Name
3-Methyladenine
Catalog #
74222
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
3-Methyladenine
Catalog #
74222
Lot #
All
Language
English

Educational Materials (4)

Protocol
How to Count Cells with a Hemocytometer
Wallchart
Small Molecules, Big Impact in Cancer Research
Wallchart
Small Molecules, Big Impact in Pluripotent Stem Cell Research
Mini Review
Small Molecules

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