Anti-Mouse CD27 Antibody, Clone LG.3A10

Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27

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From: 129 USD

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Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27
From: 129 USD

Overview

The LG.3A10 antibody reacts with CD27, a 45 - 55 kDa member of the tumor necrosis factor receptor superfamily. CD27 is found on peripheral T cells, memory B cells, and NK cells and in mice has been found on most thymocytes, except CD46-CD8- precursors. CD27 and its ligand CD70 are involved in multiple aspects of T cell biology, including the costimulation and expansion of CD4+ and CD8+ T cells and differentiation to memory CD8+ T cells. CD27 interacts with TRAF family members, resulting in enhanced cellular proliferation and the induction of anti-apoptotic proteins. Additionally, CD27 plays important roles in T cell – B cell interactions and the maturation of effector T cells. The expansion of activated B cells and their differentiation to plasma cells is also reported to be enhanced by CD27.
Subtype:
Primary Antibodies
Target Antigen:
CD27
Alternative Names:
LPFS2, S152, T14, TNFRSF7, Tp55
Reactive Species:
Human; Mouse; Rat
Conjugation:
Unconjugated; PE
Host Species:
Hamster
Cell Type:
B Cells; NK Cells; T Cells; Other
Application:
Flow Cytometry; Immunohistochemistry; Immunoprecipitation; Functional Assay
Area of Interest:
Immunology; Infectious Diseases
Clone:
LG.3A10
Gene ID:
21940/939/500318
Isotype:
IgG1, kappa

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Data and Publications

Data

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (filled histogram), or an Armenian hamster IgG isotype control antibody, followed by a goat anti-hamster (Armenian) IgG antibody, Alexa Fluor® 488 (solid line histogram).

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD27 Antibody, Clone LG.3A10, PE (filled histogram) or an Armenian hamster IgG isotype control antibody, PE (solid line histogram).

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.