Introductory Sample Request: BrainPhys™ Neuronal Medium

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Do your neurons fire together?

Your neuronal cultures should mimic the physiological conditions in the brain as closely as possible, whether you are measuring complex interactions of induced pluripotent stem (iPS) cell-derived neurons or studying rodent neuronal biology in a controlled environment. Promote, rather than inhibit, neuronal activity and maturity in your cultured primary or human pluripotent stem cell (hPSC)-derived neurons by using BrainPhys™ Neuronal Medium. Based on the formulation by Bardy and Gage (Bardy et al. PNAS, 2015), BrainPhys™ Neuronal Medium is a serum-free basal medium that is optimized to yield a higher proportion of synaptically active neurons by mimicking the extracellular environment of the central nervous system (CNS).

Use BrainPhys™ Neuronal Medium for long-term culture of hPSC- and CNS-derived neurons. To avoid shocking your cells with media changes, you can also use BrainPhys™ medium when performing functional assays, such as microelectrode array-based recordings or live-fluorescent imaging.

Why Use BrainPhys™ Neuronal Medium?

  • More representative of the brain’s extracellular environment.
  • Improved neuronal function and a higher proportion of synaptically active neurons.
  • Perform functional assays without changing media and shocking cells.
  • Supports maturation of primary and PSC-derived neurons.
  • Rigorous raw material screening and quality control ensure minimal lot-to-lot variability.