Dopamine (Hydrochloride)

Catecholamine neurotransmitter

Dopamine (Hydrochloride)

Catecholamine neurotransmitter

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Catecholamine neurotransmitter
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Overview

Dopamine is a catecholamine neurotransmitter and a beta-adrenergic and dopaminergic receptor agonist (Aslanoglou et al.; Hoban et al.; Wise). This endogenous neurotransmitter is linked to motor and motivational functions in the brain (Aslanoglou et al.; Wise). Reduction of dopamine neurons in the substantia nigra is one of the main pathological features of Parkinson’s disease (Hoban et al.). In addition, dopamine is used in applications to investigate the neurological pathways related to reward and addiction, which have implications for psychiatric disorders (Taber et al.). Dopamine also plays a role in regulating the immune response and has been implicated in tumor immunity and autoimmune diseases (Xue et al.).

CANCER RESEARCH
·Activates the JNK pathway and induces apoptosis in human kidney cells (Luo et al.).
Alternative Names
3-Hydroxy Tyramine; 3-Hydroxytyramine hydrochloride; KW 3160
Cell Type
Neurons
Area of Interest
Disease Modeling, Neuroscience
CAS Number
62-31-7
Chemical Formula
C8H11NO2 • HCl
Molecular Weight
189.6 g/mol
Purity
≥ 98%

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0887
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0887
Lot #
All
Language
English

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