Whole Exome Sequencing Reveals Selective Pressures and Dominant Negative Mutations in hPSC Cultures

View this webinar presentation by Prof. Kevin Eggan (Harvard University) and Dr. Florian Merkle (University of Cambridge) to learn more about genetic variations in human pluripotent stem cell (hPSC) cultures revealed by whole exome sequencing of more than 100 of the world’s hES cell lines, and the importance of maintaining high-quality hPSCs for regenerative medicine and other applications. The research discussed in the webinar is now published in Nature: Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Publish Date: April 19, 2017

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