Anti-Human CD33 Antibody, Clone P67.6

Mouse monoclonal IgG1 antibody against human CD33

Anti-Human CD33 Antibody, Clone P67.6

Mouse monoclonal IgG1 antibody against human CD33

From: 188 USD
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Mouse monoclonal IgG1 antibody against human CD33
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Overview

The P67.6 antibody reacts with CD33 (Siglec-3), a 67 kDa type 1 transmembrane sialoadhesin protein of the immunoglobulin superfamily. CD33 is expressed on committed myeloid progenitor cells, monocytes, granulocytes, dendritic cells, mast cells, resident macrophages, subsets of B cells, and activated T and NK cells. CD33 is a major marker used to differentiate myeloid from lymphoid or erythroid leukemias. In peripheral blood, it is expressed at high levels on monocytes and at lower levels on granulocytes. CD33 functions as a sialic acid-dependent cell adhesion molecule and mediates protein-glycan and protein-protein interactions between cells. It also has a putative role as an inhibitory receptor during the immune response.
Subtype
Primary Antibodies
Target Antigen
CD33
Reactive Species
Human
Conjugation
PE
Host Species
Mouse
Cell Type
Granulocytes and Subsets, Myeloid Cells
Species
Human
Application
Cell Isolation, Flow Cytometry
Area of Interest
Immunology
Clone
P67.6
Gene ID
945

Data Figures

Figure 1. Data for PE-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD33 Antibody, Clone P67.6, PE (filled histogram) or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, PE (Catalog #60070PE; solid line histogram).

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60126PE, 60126PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60126PE, 60126PE.1
Lot #
All
Language
English

Resources and Publications