Perhexiline Maleate

Carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor

More Views

From: 45 USD

Options

* Required Fields

Catalog # (Select a product)
Carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor
From: 45 USD

Overview

Perhexiline Maleate is an inhibitor of the mitochondrial enzymes carnitine palmitoyltransferase 1 (CPT1; IC₅₀ = 0.077 mM in rat heart; IC₅₀ = 0.148 mM in rat liver) and CPT2 (IC₅₀ = 0.079 mM in rat heart; Kennedy et al. 1996; Kennedy et al. 2000). Perhexiline Maleate also modulates autophagy via mammalian target of rapamycin complex 1 (mTORC1) signaling (Balgi et al.).

METABOLISM
· Alters myocardial metabolism from fatty acid to glucose utilization, resulting in higher ATP production and oxygen consumption (Ashrafian et al.; Jeffrey et al.).

CANCER RESEARCH
· Inhibits mTORC1 signaling and induces autophagy in MCF-7 cells (Balgi et al.).
CAS Number:
6724-53-4
Chemical Formula:
C₁₉H₃₅N • CHO
Molecular Weight:
393.6 g/mol
Purity:
≥ 95%
Target:
CPT1; CPT2

Scientific Resources

Product Documentation

Document Type
Product Name
Catalog #
Lot #
Language
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.