Human Recombinant IL-22

Interleukin 22

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Human Recombinant IL-22

Interleukin 22

From: 673 USD

Size

50 µg

Catalog #

(Select a product)

Interleukin 22

Quantity

Add to Wish List

Request Pricing

Thank you for your interest in this product. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

Estimated delivery time for your area

Product sample or exclusive offer

In-lab demonstration

By submitting this form, you are providing your consent to STEMCELL Technologies Canada Inc. and its subsidiaries and affiliates (“STEMCELL”) to collect and use your information, and send you newsletters and emails in accordance with our privacy policy. Please contact us with any questions that you may have. You can unsubscribe or change your email preferences at any time.

Overview

Interleukin 22 (IL-22) is a class 2 α-helical cytokine that signals through the class 2 cytokine receptor and activates the JAK/STAT pathway. IL-22 is secreted by Th1, Th2, Tc22, and γδ T cells, dendritic, mast and NK cells. It stimulates expression of antimicrobial peptides from epithelial cells, thus hindering bacterial infections. Depending on the interactions with other cytokines, IL-22 can either promote inflammation or prevent tissue destruction by regulating host defense and tissue homeostasis at barrier surfaces (Sonnenberg et al.).

Cytokines

Airway Cells, Hepatic Cells, Intestinal Cells, Keratinocytes, T Cells, T Cells, CD4+, T Cells, CD8+

Human

Epithelial Cell Biology, Immunology

> 98%

Data Figures

(A) The biological activity of Human Recombinant IL-22 was tested by its ability to produce IL-10 in COLO 205 cells. IL-10 secretion was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is less than 1 ng/mL.
(B) 2 μg of Human Recombinant IL-22 was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant IL-22 has a predicted molecular mass of 16.9 kDa.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type

Product Name

Catalog #

Lot #

Language

Document Type

Product Information Sheet

Product Name

Human Recombinant IL-22

Catalog #

78038

Lot #

All

Language

English

Document Type

Safety Data Sheet

Product Name

Human Recombinant IL-22

Catalog #

78038

Lot #

All

Language

English

Resources and Publications

Related Products

Quality Statement:

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.

Human Recombinant IL-22

Interleukin 22

Human Recombinant IL-22

Interleukin 22

Request Pricing

Overview

Data Figures

Protocols and Documentation

Resources and Publications

Educational Materials (3)

Related Products

Item added to your cart