Modeling Arrhythmias Using hPSC-Derived Cardiomyocytes and Tracking Their Excitability

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Join our live webinar with Drs. Vincenzo Macri and Stacie Chvatal as they discuss their current work on tools to generate human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) and to measure these cells’ excitability. These tools enable modeling of arrhythmias using patient-derived and gene-edited hPSC lines associated with genetic mutations and drug-acquired arrhythmias. In this webinar, Dr. Vincenzo Macri will present a complete workflow for efficient generation of hPSC-CMs using the STEMdiff™ Cardiomyocyte System and the modeling of cardiac arrhythmias. Dr. Stacie Chvatal will present on the measurement, tracking and high-throughput analysis of multiple hPSC-CM lines simultaneously using the Maestro™ microelectrode array (MEA) system.


Senior Scientist
STEMCELL Technologies Inc.

Vincenzo Macri, PhD, is a Senior Scientist at STEMCELL Technologies, developing products to support cardiomyocyte stem cell research. Dr. Macri completed his PhD in Physiology from the University of British Columbia. He then worked as a Postdoctoral Research Fellow at the Massachusetts General Hospital and Harvard Medical School. His areas of study included human genetics, cardiac arrhythmias, cellular electrophysiology and cardiomyocyte stem cell biology.

Senior Application Scientist
Axion BioSystems

Stacie Chvatal, PhD, is a Senior Application Scientist at Axion BioSystems and plays a leading role in developing Axion’s CiPA Analysis Tool to streamline MEA cardiac analysis. Dr. Chvatal completed her PhD in Biomedical Engineering from the Georgia Institute of Technology and Emory University. She then continued her research as a Postdoctoral Fellow at Georgia Tech. Her research was in neural control movement in healthy and impaired nervous systems of humans and animals.

Live Webinar - Modeling Arrhythmias Using hPSC-Derived Cardiomyocytes and Tracking Their Excitability

Wednesday, August 2nd, 2017 - 10 AM PDT | 1 PM EDT | 6 PM BST

If you are unable to attend the live webinar, please register and we will send you a link to view the recording when it becomes available.


Topics
  • Overview of the generation of cardiomyocytes from hPSCs
  • In vitro modeling of cardiac arrhythmias using cardiomyocytes generated from genetically engineered and patient-derived hPSCs
  • Microelectrode array technology to assess the electrophysiological properties of hPSC-derived cardiomyocytes