“Viral Pathogens” Featuring Dr. James Crowe
On this episode of the Immunology Podcast, Dr. James Crowe talks about his team's work on the first known case of COVID-19 in the USA, the versatility of monoclonal antibodies for disease prevention and treatment, and preparing for the next pandemic.
Dr. James Crowe is the Director of the Vanderbilt Vaccine Center, which uses molecular and cellular biology, state-of-the-art imaging and flow cytometry, bioinformatics, and bioengineering approaches to study major human pathogens. He talks about his monoclonal antibody discovery program for COVID-19 and other viruses.
It was fascinating to learn about Dr. Crowe’s quest to generate monoclonal antibody therapeutics for every viral infection, which can be invaluable tools against emerging diseases.
Dr. Brenda Raud, host
Find more episodes at immunologypodcast.com or wherever you get your podcasts.
This Episode's Immunology Roundup:
- COVID-19 Vaccine Effectiveness Against the Delta Variant – The Pfizer and Astrazeneca vaccines are highly protective against the delta variant of COVID-19 after two doses.
- Immune Cell Mechanisms in Colitis – Researchers identified an inverse correlation between inflammatory bowel disease severity and Cox2 expression, uncovering an active immune pathway that may be targeted to reduce inflammation.
- T Cell Specificity in Melanoma – Scientists took an in-depth look at the relationship between T cell receptors and T cell phenotypes in patient-derived melanoma cell lines.
- Overcoming PD-1 Blockade Resistance in Lung Cancer – Researchers studied the transcriptional programs of neoantigen-specific tumor-infiltrating lymphocytes in anti-PD-1-treated lung cancers.
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