“Post-Implantation Blastoids” Featuring Drs. Thorold Theunissen and Rowan Karvas
Dr. Thorold Theunissen is an Assistant Professor of Developmental Biology at Washington University in St. Louis, investigating the molecular basis of pluripotency, the mechanisms of trophoblast development, and the generation of stem cell-based embryo models. Dr. Rowan Karvas is a CRM Fellow in Regenerative Medicine working in the Theunissen lab. They talk about their recent work developing 3D-cultured blastoids and how they could be used to study pregnancy-related diseases and infertility.
Drs. Theunissen and Karvas have recently published a Cell Stem Cell article pushing the boundaries of what's possible in early human embryo modeling, the hottest area (in my opinion) in stem cell biology. A very unique chat about a hot-off-the-press paper!
Dr. Arun Sharma, host
Find more episodes at stemcellpodcast.com or wherever you get your podcasts.
This Episode's Stem Cell Roundup:
- Lab-Grown Human Embryos – Researchers created structured stem cell-based embryo models and grew them outside the womb for 14 days post-fertilization.
- A Human Model for Autism – Scientists developed a single-cell brain organoid screen to identify developmental defects in autism.
- Semi-Human Kidneys in Pigs – Researchers successfully grew kidneys containing human cells in pig embryos.
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