"Pathogens, Autoantigens, and Antigens" Featuring Dr. Frances Lund

On this episode of the Immunology Podcast, Dr. Frances Lund discusses the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses.

Dr. Frances Lund is the Charles H. McCauley Professor and Chair of the Department of Microbiology at the University of Alabama at Birmingham. Her lab showed that B cells not only make antibodies, but also produce cytokines that modulate the microenvironment. She currently studies the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses.

The work of Dr. Lund shows that B cells are far more than just antibody factories—they are critical for immune homeostasis!

Dr. Jason Goldsmith, host

Find more episodes at immunologypodcast.com or wherever you get your podcasts.

This Episode's Immunology Roundup:

  • A COVID-19 Vaccine Targeting CD40 – Researchers fused a CD40 monoclonal antibody to a SARS-CoV-2 protein, which stimulated dendritic cells and boosted the immune response of monkeys already exposed to the virus.
  • A T Cell Cancer Vaccine – Scientists generated a therapeutic cancer vaccine by genetically modifying T cells to deliver antigens and adjuvant signals to lymphoid tissues.
  • Dendritic Cells in Intestinal Immunity – Intestinal dendritic cells have local specializations that depend on the microenvironment.
  • Stress and the Immune System – Psychological stress primes monocytes to an inflammatory state.
Publish Date: March 16, 2022

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