"Lymphocyte Activation" Featuring Dr. Marc Jenkins

On this episode of the Immunology Podcast, Dr. Marc Jenkins discusses his work investigating CD4+ T and B cell activation in vivo by directly tracking antigen-specific cells.


Dr. Marc Jenkins is a Regents and Distinguished McKnight University Professor in the Department of Microbiology and Immunology and the Director of the Center for Immunology at the University of Minnesota. Dr. Jenkins discovered that CD4+ T cells require CD28 as well as TCR to produce IL-2. His lab investigates CD4+ T and B cell activation in vivo by directly tracking antigen-specific cells.

It was an absolute pleasure talking with Dr. Jenkins, and hearing about his journey to understand T-helper cell differentiation and activation. It was a pleasure to be able to talk with such a legend of the immunology community.

Dr. Jason Goldsmith, host

Find more episodes at immunologypodcast.com or wherever you get your podcasts.

This Episode's Immunology Roundup:

  • A Pathway to Regulate T Follicular Helper Cells – Scientists identified a metabolic control pathway that regulates T follicular helper cells and humoral immunity.
  • HIV Treatment and the Microbiome – Researchers found that in HIV patients treated with combined antiretroviral therapy, the composition of the microbiome fluctuates and affects the reconstitution of CD4 T cells.
  • Blocking RSV Replication – A drug that hardens viral inclusion bodies inhibited respiratory syncytial virus replication in mice.
  • COVID-19 Vaccine-Induced Blood Clots – Adenoviral vector vaccines can induce platelet activation that can contribute to thrombosis by producing antibodies that bind to platelet factor 4.
Publish Date: August 14, 2021

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