(S)-MG132
Ubiquitin-proteasome inhibitor; NF-kB pathway inhibitor; IκB activator
Overview
CANCER RESEARCH
· Blocks apoptosis triggered by DNA damage in HeLa cells (Zhang et al.).
· Inhibits NF-κB activation, sensitizing a variety of carcinoma cell lines to apoptosis (Arlt et al.).
· Cytotoxic effects on a variety of human cancer cell lines (Banerjee & Liefshitz).
· Inhibits growth of mouse melanoma (B16) and human ocular melanoma (IPC227F) cell lines (Vivier et al.).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Resources and Publications
Educational Materials (2)
Publications (8)
Abstract
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Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.