• Compare Products
Menu
Account
Explore the new wish list functionality on our website, which lets you organize products into wish lists, view your saved products, and share them with others. Sign in or create an account to access this feature. Explore the new wish list functionality on our website. Sign in or create an account to access this feature.

Atazanavir

HIV-1 protease inhibitor

Loading...
 

Atazanavir

HIV-1 protease inhibitor

From: 559 USD
Catalog #
(Select a product)
HIV-1 protease inhibitor
Add to Wish List

Overview

Inhibit HIV-1 protease with atazanavir (IC50 = 2 - 5 nM; Wood). Atazanavir, an azapeptide, binds to HIV-1 protease and prevents it from producing viral proteins, rendering the virus non-infectious, as no mature virions are made when HIV-1 protease is inhibited (Kohl et al.). Atazanavir is also a substrate and an inhibitor of cytochrome P450 isozyme 3A (CYP3A), and an inducer of P-glycoprotein (Perloff et al.).

Atazanavir has been used for:

CANCER RESEARCH
· Induces endoplasmic reticulum stress response in malignant glioma cells by activating caspase-4, which leads to cell death (Pyrko et al.).
· Induces senescence and oxidative stress in proliferating human bone marrow mesenchymal stem cells (Hernandez-Vallejo et al.).
Alternative Names
BMS 232632; CGP 73547; Latazanavir
Cell Type
Cancer Cells and Cell Lines
Area of Interest
Cancer
CAS Number
198904-31-3
Chemical Formula
C38H52N6O7
Molecular Weight
704.9 g/mol
Purity
≥ 98%

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Atazanavir
Catalog #
100-1166
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Atazanavir
Catalog #
100-1166
Lot #
All
Language
English

Resources and Publications

Educational Materials (3)

Small Molecules for Your Research
Brochure
Small Molecules for Your Research
Small Molecules, Big Impact in Cancer Research
Wallchart
Small Molecules, Big Impact in Cancer Research
Small Molecules
Mini Review
Small Molecules

Quality Statement:

PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.

Copyright © 2024 by STEMCELL Technologies. All rights reserved.