Human Recombinant Visfatin

Visfatin

Human Recombinant Visfatin

Visfatin

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Visfatin
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Overview

Use visfatin to catalyze the production of nicotinamide mononucleotide from nicotinamide (Revollo et al.). Nicotinamide mononucleotide is a precursor to nicotinamide adenine dinucleotide (NAD) that is vital to energy metabolism, cell death, and other cellular processes (Ying). Visfatin also acts as an immunomodulator by activating leukocytes and inducing the production of pro-inflammatory and anti-inflammatory cytokines (Moschen et al.), and there is evidence that visfatin can regulate insulin receptor signaling and insulin secretion (Brown et al.). Belonging to the nicotinate phosphoribosyltransferase (NAPRTase) family, Visfatin is an adipokine that is produced in adipocytes, leukocytes, and hepatocytes (Chiu et al., Garten et al., Kralisch et al.). It is active as a homodimer with each identical monomer consisting of two structural domains made up of 19 β-strands and 13 α-helices (Kim et al.). For consistency and reproducibility across your applications, visfatin from STEMCELL comes lyophilized with ≥ 90% purity, and is verified by LAL analysis to ensure endotoxin levels are ≤ 1.0 EU/μg protein.
Subtype
Cytokines
Alternative Names
NAMPT, PBEF, PBEF1
Species
Human
Area of Interest
Metabolism
Purity
≥ 90%

Data Figures

Human Recombinant Visfatin was resolved with SDS-PAGE under reducing (+) conditions and visualized by Coomassie Blue staining. Human Recombinant Visfatin has a predicted molecular mass of 52.7 kDa.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-1335
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-1335
Lot #
All
Language
English