Human Recombinant CCL19 (MIP-3 beta)

Chemokine ligand 19 or macrophage inflammatory protein-3 beta

Human Recombinant CCL19 (MIP-3 beta)

Chemokine ligand 19 or macrophage inflammatory protein-3 beta

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Chemokine ligand 19 or macrophage inflammatory protein-3 beta
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Overview

Chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein-3 beta (MIP-3β), is a member of the CC chemokine family, which plays key roles in inflammatory responses, T cell activation, homeostasis, and development (Yan et al.). CCL19 is expressed in lymph nodes, thymus, and activated bone marrow stromal cells; it binds to C-C motif chemokine receptor 7 (CCR7) to induce migration of macrophages, T cells, and B cells (Gibejova et al.). Clinically, the expression of CCL19 is correlated to autoimmune diseases such as rheumatoid arthritis and cancer (Pickens et al.; Zhang et al.).
Alternative Names
beta-chemokine exodus-3, CC chemokine ligand 19, ELC, Exodus-3, MIP-3β, SCYA19
Cell Type
B Cells, Macrophages, T Cells
Species
Human
Area of Interest
Immunology
Purity
≥ 95%

Data Figures

Figure 1.

Human Recombinant CCL19 (MIP-3 beta) was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant CCL19 (MIP-3 beta) has a predicted molecular mass of 8.8 kDa.

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0935
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0935
Lot #
All
Language
English

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