Eltrombopag

Thrombopoietin receptor agonist

More Views

From: 25 USD

Options

* Required Fields

Catalog # (Select a product)
Thrombopoietin receptor agonist
From: 25 USD

Overview

Eltrombopag is a thrombopoietin receptor (TpoR) agonist (EC₅₀ = 0.27 µM in a reporter assay) and an iron chelator (Erickson‐Miller et al.). Interaction between Eltrombopag and TpoR triggers proliferation and differentiation of human bone marrow progenitor cells into megakaryocytes and increases platelet growth and production (Erickson‐Miller et al.).

DIFFERENTIATION
· Stimulates proliferation and differentiation of primary human CD34+ bone marrow cells into CD41+ megakaryocytes (Erickson‐Miller et al.).
Alternative Names:
SB497115
CAS Number:
496775-61-2
Chemical Formula:
C₂₅H₂₂NO
Molecular Weight:
442.5 g/mol
Purity:
≥ 98%
Pathway:
STAT5
Target:
TpOR

Scientific Resources

Product Documentation

Document Type
Product Name
Catalog #
Lot #
Language
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.