Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene
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Stem Cell Research 2016 MAY
Abstract
Human iPSC line L749.1 was generated from fibroblasts of a patient with Leigh syndrome associated with a heteroplasmic mutation in the MT-ATP6 gene. Reprogramming factors OCT4, SOX2, CMYC and KLF4 were delivered using retroviruses.
