Vps34-IN1
Vps34 inhibitor
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Vps34-IN1 -
Vps34-IN1 -
Label for Vps34-IN1 -
Label for Vps34-IN1
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Overview
Vps34-IN1 is a potent and reversible inhibitor (IC₅₀ = 25 nM) of vacuolar protein sorting 34 (Vps34), a class II phosphoinositide 3-kinase that regulates autophagosome formation (Bago et al.).
CANCER RESEARCH
· Reduces accumulation of phosphorylated phosphatidylinositol (PtdIns(3)P) at endosomal membranes (Bago et al.).
CANCER RESEARCH
· Reduces accumulation of phosphorylated phosphatidylinositol (PtdIns(3)P) at endosomal membranes (Bago et al.).
Alternative Names:
Vacuolar Protein Sorting 34 Inhibitor 1; Vps34 Inhibitor 1
CAS Number:
1383716-33-3
Chemical Formula:
C₂₁H₂₄ClN₇₀
Molecular Weight:
425.9 g/mol
Purity:
≥ 98%
Pathway:
PI3K/AKT
Target:
Vps34
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