Toxicity testing is paramount when screening newly developed drugs to advance them through the development pipeline. Using the right cell-based models and assays for such testing in the early stages of your research can help reduce late-stage attrition.
STEMCELL Technologies is here to bolster your drug development and toxicity testing research. With personalized services, custom products, flexible delivery times, and the option to reserve entire lots to pre-screen cells for applications, we help you get the ethically sourced, human primary cells you need. In addition, our Contract Assay Services (CAS) specialize in primary cell-based assays and can work with you to design and perform your drug development studies.
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Contract Out Your In Vitro Assays
Contract Assay Services (CAS) combines the power of specialized STEMCELL products with the practical knowledge of our scientists to provide both standardized and customized assay services. Partner with our in-house contract research organization (CRO) to obtain timely, high-quality, and clinically relevant data.
In vitro testing on primary cells allows you to preview in vivo responses, facilitating design of better dosing strategies and optimization of animal models in preclinical testing, as well as phase I clinical trials. We specialize in performing in vitro assays to assess hematotoxicity and mesenchymal toxicity to help you measure the potential toxic effects of candidate therapeutics, including small molecule compounds and biologics.
Let us help you evaluate preclinical test compounds and biologics for their abilities to modulate the immune system. We offer customized cell-based assays based on your specific needs and can help you design studies to evaluate the effects of potential immunomodulatory agents using fresh or frozen cell samples.
Biopharmaceutical and Biosimilar Assessment Services
Biopharmaceutical drugs, also known as biologics, have become an essential part of modern pharmacotherapy and include examples such as biological proteins, cytokines, hormones, monoclonal antibodies, vaccines, and cell- and tissue-based therapies. Test the activity of your biopharmaceutical cytokines efficiently with our hematopoietic colony-forming cell (CFC) or colony-forming unit (CFU) assay services.
If you work with human primary cells*, you know how important sourcing the right product for your research is. As part of our commitment to helping you find ethically sourced cells and workflows approved for use in your applications, we recently launched these new products.
Get large numbers of fresh or frozen mononuclear cells from a selection of leukopak sizes.
Immune Cell Subsets**
Schedule delivery of fresh pan-T cells, B cells, NK cells, and more— at your convenience.
Human PB CD19+CD27+ Memory B Cells, Frozen
Choose ready-to-use, ethically sourced, primary human CD19+CD27+ memory B cells with or without donor-matched CD19+CD27- naïve B cells for in vitro research applications.
Cancer-Sourced Human PB Products
Choose ethically sourced, peripheral blood mononuclear cells (PBMCs), plasma, and serum from donors diagnosed with prostate cancer, leukemia, lymphoma, and other cancer types.
Human Platelet Lysate, Fibrinogen-Depleted, GMP-Compliant
Streamline your cell-based assays with ethically sourced, fibrinogen-depleted, GMP-compliant human platelet lysate.
Access fresh leukocytes that can be further processed for the isolation of various cell subsets.
Human PB Serum, Fresh or Frozen
Get fresh or frozen human PB serum for maintenance and expansion of your cells.
ImmunoCult™ T Cell Activators
Gently activate and expand human T cells without the use of magnetic beads, feeder cells, or antigen.
ImmunoCult™ XF T Cell Expansion Medium
Culture and expand T cells in serum-free and xeno-free medium.
STEMdiff™ T Cell Kit
Obtain high yields of T cells from human pluripotent stem cells (hPSCs).
Streamline your large-scale cell isolations with the efficiency and throughput of RoboSep™-C, and process entire leukopaks in 65 minutes.
Magnetically label and separate virtually any cell type by positive or negative selection using RoboSep™-S—for fully automated cell separation.
Standardize Your Cell Thawing Process
Increase confidence in your cell thawing workflow, by ensuring sample sterility and consistent thawing performance, with ThawSTAR®—a sensor-based automated thawing system.
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