Protocol Resources for Red Blood Cell Removal

Cell Separation Methods

Red Blood Cell Removal

When isolating specific cell types from blood for functional studies or downstream assays, red blood cell (RBC) depletion may be required. Here are technical tips and protocols on how to deplete RBCs from blood samples prior to cell separation, including how to remove RBCs from different types of blood samples and how to deplete RBCs without ammonium chloride lysis.

Learn about cell isolation from blood >


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