“Cell Science at the Allen Institute” Featuring Drs. Ru Gunawardane and Kaytlyn Gerbin
On this episode of the Stem Cell Podcast, Drs. Ru Gunawardane and Kaytlyn Gerbin at the Allen Institute for Cell Science discuss the Institute’s mission to understand the fundamentals of how cells work, how they generate their gene-edited stem cell lines, and their recent work tracking cell states in hiPSC-derived cardiomyocytes.
Dr. Ru Gunawardane is the Executive Director at the Allen Institute for Cell Science. She leads a group of researchers creating a collection of high-quality gene-edited stem cell lines to study cell organization and activities through live cell imaging. Dr. Katylyn Gerbin is a Scientist at the Allen Institute, whose work focuses on implementing cardiac differentiation methods and developing the cardiomyocyte pipeline using gene-edited hiPSCs. They discuss the Institute’s mission to understand the fundamentals of how cells work, how they generate their gene-edited stem cell lines, and their recent work tracking cell states in hiPSC-derived cardiomyocytes.
On this episode of the podcast, we chat with two cardiomyocyte imaging experts, Drs. Ru Gunawardane and Kaytlyn Gerbin from the Allen Institute for Cell Science. Their fluorescently tagged iPSC lines enable exquisite real-time imaging and analyses of cellular function.
Dr. Arun Sharma, host
Find more episodes at stemcellpodcast.com or wherever you get your podcasts.
This Episode's Stem Cell Roundup:
- SARS-CoV-2 Induces Fibrosis in Kidney Cells and Organoids – SARS-CoV-2 can directly infect kidney cells, inducing cell injury with subsequent fibrosis.
- SFluctuating Methylation Clocks for Cell Lineage Tracing – Researchers used fluctuating DNA methylation sites to track the ancestry and dynamics of a cell population.
- Forebrain Assembloid Models of Timothy Syndrome – Scientists used forebrain assembloids to study interneuron migration in Timothy syndrome.
- Lineage Tracing in Cerebral Organoid Development – Researchers used iTracer, a lineage recorder, to explore clonality and lineage dynamics during cerebral organoid development.
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