The intestinal epithelium is a rapidly renewing tissue that can undergo complete cellular replacement every four to five days. These regenerative properties make the intestinal epithelium an attractive system for researchers studying epithelial regeneration, adult stem cell biology, disease modelling and cancer biology, both within and outside the context of the intestine.
Explore the resources below for information to support your intestinal research and the growth of intestinal organoids.
Global organoid experts gathered in London, UK to discuss the current state of the technology, protocol standardization, translation into patient care, nomenclature, and understanding what questions a given organoid culture can and can't answer.Read Now >
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Overview of the intestinal stem cell niche, major cell types and signaling pathways
Overview of gastrointestinal tract specification signals and summary of pancreatic cellular hierarchy and cell markers
Key culture conditions and organoid-forming cells from a variety of epithelial tissues