“Immunological Memory” Featuring Dr. Susan Kaech

Dr. Susan Kaech is a Professor and Director of the NOMIS Center for Immunobiology and Microbial Pathogenesis at the Salk Institute. Her lab aims to understand how memory T cells are produced during infection and vaccination, how they function, and why they can fail to induce long-term immunity, particularly during chronic disease or cancer. In this episode, she talks about her research on T cell exhaustion and neuroimmunology, as well as her path from genetics to immunology.

In this episode, we talk to one of the foundational titans of immune memory, Dr. Susan Kaech. Don’t miss it!

Dr. Jason Goldsmith, co-host

Find more episodes at immunologypodcast.com or wherever you get your podcasts.

This Episode's Immunology Roundup:

  • Glycan Breakdown and Bacterial Function – Researchers used a large-scale screen to identify enzyme systems that represent an underappreciated mode of glycan degradation.
  • Cancer Risk After CAR T Therapy – Only a small percentage of patients who receive CAR T therapies develop secondary cancers, and most are not directly linked to CAR T treatment.
  • CD8+ T Cells in Hepatitis B – Hepatocellular priming induces key co-signaling receptors in dysfunctional CD8+ T cells.
  • T Cell Aging - T cell epigenetic clocks measure replicative history and can continue to accumulate well beyond organismal lifespan.
Publish Date: October 07, 2024