Dr. Martin Pera from the Jackson Laboratory and International Stem Cell Initiative (ISCI) discusses the biological effects of recurrent genetic variants that arise in human pluripotent stem cells (hPSCs) in culture and during differentiation. This presentation and the following Q&A session were moderated by Dr. Peter Andrews from the University of Sheffield. This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here. Note: Some original data from this presentation has been omitted to abide by copyright rules.
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