SU5402
MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
Overview
SU5402 is a potent and selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), fibroblast growth factor receptor 1 (FGFR-1), and platelet-derived growth factor receptor beta (PDGFRB) with IC50 = 0.02, 0.03, and 0.51 µM, respectively (Sun et al.).
Alternative Names
Not applicable
Cell Type
Cancer Cells and Cell Lines, Hybridomas, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Maintenance
Area of Interest
Antibody Development, Cancer, Disease Modeling, Hybridoma Generation, Immunology, Stem Cell Biology
CAS Number
215543-92-3
Chemical Formula
C₁₇H₁₆N₂O₃
Molecular Weight
296.3 g/mol
Purity
≥ 95%
Pathway
MEK/ERK
Target
FGFR, PDGFR
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet 1
Product Name
SU5402
Catalog #
73912, 73914 Lot #
For orders placed 2019-11-26 or earlier Language
English Document Type
Product Information Sheet 2
Product Name
SU5402
Catalog #
73912, 73914 Lot #
For orders placed 2019-11-27 or later Language
English Document Type
Safety Data Sheet
Product Name
SU5402
Catalog #
73912, 73914 Lot #
All Language
English Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for
B Cell Research
Workflow Stages for
Hybridoma Production
Workflow Stages for
Mouse Pluripotent Stem Cell Research
Resources and Publications
Educational Materials (4)
Related Products
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Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
