Pteryxin

Inhibits butyrylcholinesterase

Pteryxin

Inhibits butyrylcholinesterase

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Inhibits butyrylcholinesterase
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Overview

Pteryxin is a dihydropyranocoumarin derivative that potently inhibits butyrylcholinesterase (IC50 = 12.96 μM; Orhan et al.). Butyrylcholinesterase is involved in the regulation of acetylcholine in the brain, and its activity level is higher in patients with Alzheimer's disease (Greig et al.). Butyrylcholinesterase inhibitors have been implicated as lead compounds for developing treatment for Alzheimer's disease (Orhan et al.).

IMMUNOLOGY
· Blocks the production of lipopolysaccharide (LPS)-induced nitric oxide in macrophages (IC50 = 20 µM; Matsuda et al.).
Alternative Names
Pterixin; (+)-Pteryxin; Pteryxine
Cell Type
Neurons
Area of Interest
Disease Modeling, Immunology, Neuroscience
CAS Number
13161-75-6
Chemical Formula
C21H22O7
Molecular Weight
386.4 g/mol
Purity
≥ 98%

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
Pteryxin
Catalog #
100-0897
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Pteryxin
Catalog #
100-0897
Lot #
All
Language
English