Collagenase Type II

For digestion of native collagen fibrils

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For digestion of native collagen fibrils
From: 74 USD

Overview

Collagenase is a protease consisting of a single polypeptide chain approximately 1,000 amino acid residues in length. Collagenase is capable of digesting native collagen fibrils commonly found in connective tissues and therefore is frequently used for tissue dissociation. Collagenase preparations contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). Collagenase Type II contains high levels of protease activity, especially clostripain, and has been used for the digestion of lung (You & Brody; Comhair et al.), kidney (Valente et al.), liver (Linghor et al.), thymus (Vandenabeele et al.), endothelial cells (Patel et al.) and mesenchymal stem cells (Steigman & Fauza).
Subtype:
Enzymatic
Alternative Names:
Clostridium histolyticum collagenase; Collagenase 2; Collagenase Type 2; Collagenase II
Cell Type:
Mesenchymal Stem and Progenitor Cells; Hepatic Cells; Endothelial Cells; T Cells, CD4+
Species:
Human; Mouse; Non-Human Primate; Other; Rat
Area of Interest:
Endothelial Cell Biology; Cancer Research; Epithelial Cell Biology; Immunology; Stem Cell Biology
Molecular Weight:
68 - 130 kDa

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STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.