(Z)-4-Hydroxytamoxifen

Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor

(Z)-4-Hydroxytamoxifen

Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor

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Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor
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Overview

(Z)-4-Hydroxytamoxifen is a cell-permeable selective estrogen receptor modulator (SERM) that binds to estrogen receptors (ER) and estrogen-related receptors (ERR) with both estrogenic and anti-estrogenic effects (Poulin et al.).


CANCER RESEARCH
· Suppresses tumor growth in breast cancer cells (Freiss et al.; Osborne et al.).
Cell Type
Cancer Cells and Cell Lines
Species
Human, Mouse, Non-Human Primate, Other, Rat
Area of Interest
Cancer
CAS Number
68047-06-3
Chemical Formula
C₂₆H₂₉NO₂
Purity
≥ 98%
Pathway
Estrogen
Target
ER

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
74056, 74054, 74052
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
74056, 74054, 74052
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.