L-DOPA

Dopamine precursor

L-DOPA

Dopamine precursor

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Dopamine precursor
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Overview

L-DOPA exhibits analgesic properties and is a precursor of dopamine (Mena et al.; Park et al.; Rekdal et al.). It has also been the gold standard in Parkinson’s disease treatments for over 50 years. It selectively crosses the blood-brain barrier, whereas dopamine cannot (LeWitt). L-DOPA lowers the number of tyrosine hydroxylase-positive neurons in fetal rat midbrain (Mena et al.).

DISEASE MODELING
· Prevents peripheral synthesis of dopamine from levodopa when co-administered with carbidopa and levodopa in rats (Park et al.).
Alternative Names
3,4-Dihydroxyphenylalanine; Levodopa
Area of Interest
Disease Modeling, Neuroscience
CAS Number
59-92-7
Chemical Formula
C9H11NO4
Molecular Weight
197.2 g/mol
Purity
≥ 95%

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
L-DOPA
Catalog #
100-0890
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
L-DOPA
Catalog #
100-0890
Lot #
All
Language
English