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Small Molecules

  • Featured CHIR99021

    CHIR99021

    WNT pathway activator; Inhibits GSK3
  • Featured Dorsomorphin

    Dorsomorphin

    BMP and AMPK pathway inhibitor; Inhibits ALK2, ALK3, ALK6, and AMPK
  • Featured Y-27632 (Dihydrochloride)

    Y-27632

    RHO/ROCK pathway inhibitor; Inhibits ROCK1 and ROCK2
  • Featured SB431542

    SB431542

    Activin/BMP/TGF-β pathway inhibitor; Inhibits ALK4, ALK5, and ALK7
  • Featured UM729

    UM729

    Pyrimido-indole derivative that enhances HSC self-renewal in vitro
  • Featured UM171

    UM171

    Pyrimido-indole derivative that enhances HSC self-renewal in vitro
  • AICAR

    AICAR

    AMPK activator
  • Sirtinol

    Sirtinol

    Epigenetic modifier; Inhibitor of Sir2p, SIRT1, and SIRT2
  • (+)-Bay K8644

    (+)-Bay K8644

    L-type calcium channel inhibitor
  • (-)-Blebbistatin

    (-)-Blebbistatin

    Non-muscle myosin II (NM II) ATPase inhibitor
  • (-)-Epigallocatechin Gallate

    (-)-Epigallocatechin Gallate

    Antioxidant and epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)
  • (-)-Indolactam V

    (-)-Indolactam V

    Protein kinase C (PKC) activator
  • (S)-MG132

    (S)-MG132

    Ubiquitin-proteasome inhibitor; NF-kB pathway inhibitor; IκB activator
  • Flurbiprofen

    (±)-Flurbiprofen

    PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2
  • (±)-Nutlin-3

    (±)-Nutlin-3

    p53 pathway activator; Inhibits MDM2
  • 1-Oleoyl Lysophosphatidic Acid (Sodium Salt)

    1-Oleoyl Lysophosphatidic Acid

    Lysophosphatidic acid (LPA)1 and LPA2 agonist
  • 16,16-Dimethyl Prostaglandin E2

    16,16-Dimethyl Prostaglandin E2

    Prostanoid pathway activator; Inhibits 15-hydroxy PGDH
  • 3-Deazaneplanocin A

    3-Deazaneplanocin A

    Epigenetic modifier; Inhibits histone EZH2 lysine methyltransferase
  • 5-Azacytidine

    5-Azacytidine

    Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)
  • 8-Bromo-cAMP

    8-Bromo-cAMP

    cAMP pathway activator; Activates cAMP-dependent kinase
  • 9-cis Retinoic Acid

    9-cis Retinoic Acid

    Retinoid pathway activator; Activates retinoic acid receptor (RAR) and retinoid X receptor (RXR)
  • A 83-01

    A 83-01

    Activin/NODAL/TGF-β pathway inhibitor; Inhibits ALK5, ALK4, and ALK7
  • A769662

    A769662

    AMPK activator
  • AG-490

    AG-490

    Tyrosine kinase inhibitor; Inhibits EGFR, HER2, JAK2, JAK3 and STAT5a/b
  • AGK2

    AGK2

    Epigenetic modifier; Inhibits SIRT2 histone deacetylase
  • AKT Inhibitor VIII

    AKT Inhibitor VIII

    PI3K/AKT pathway inhibitor; Inhibits AKT1, AKT2, AKT3
  • AKT Inhibitor X (Hydrochloride)

    AKT Inhibitor X

    PI3K/AKT pathway inhibitor; Inhibits AKT
  • All-Trans Retinoic Acid

    All-Trans Retinoic Acid

    Retinoid pathway activator; Activates retinoic acid receptor (RAR)
  • AM580

    AM580

    Retinoid pathway activator; Activates retinioc acid receptor (RAR) alpha
  • Anacardic Acid

    Anacardic Acid

    Epigenetic modifier; Inhibits histone acetyltransferase (HAT)
  • Arbidol

    Arbidol

    Blocks fusion between virus and target host cells
  • AZ628​

    AZ628​

    MEK/ERK pathway inhibitor; Inhibits B-RAF, B-RAFV600E and C-RAF-1
  • AZD6244

    AZD6244

    MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2
  • AZD8055

    AZD8055

    mTOR pathway inhibitor; Inhibits mTOR
  • BI-D1870

    BI-D1870

    90 kDa ribosomal S6 kinase (RSK) inhibitor
  • BIO

    BIO

    WNT pathway activator; Inhibits GSK3
  • BIO-Acetoxime

    BIO-Acetoxime

    WNT pathway activator; Inhibits GSK3
  • BIRB-796

    BIRB-796

    p38 MAPK inhibitor
  • BIX01294 (Trihydrochloride Hydrate)

    BIX01294

    Epigenetic modifier; Inhibits G9a histone methyltransferase
  • BMS 493

    BMS 493

    Retinoid pathway activator; Activates pan-retinoic acid receptor
  • Brefeldin A

    Brefeldin A

    Protein trafficking inhibitor; Inhibits Sec7-containing guanine-exchange factor (GEF)
  • Butein

    Butein

    NF-κB Pathway Inhibitor; Stabilizes IκB
  • Calcitriol

    Calcitriol

    Vitamin D receptor activator
  • Cardiogenol C (Hydrochloride)

    Cardiogenol C

    Inducer of cardiac differentiation
  • CAY10512

    CAY10512

    NF-κB pathway inhibitor; Inhibits NF-κB
  • CAY10585

    CAY10585

    Hypoxia inducible factor-1α (HIF1α) inhibitor
  • CAY10603

    CAY10603

    Epigenetic modifier; Inhibits histone deacetylase (HDAC) 6
  • CD437

    CD437

    Retinoid pathway activator; Activates retinoic acid receptor (RAR)