iCell® Motor Neurons Kit, 01279

Motor neurons derived from human iPS cells, frozen

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Motor neurons derived from human iPS cells, frozen
From: 595 USD

Overview

iCell® Motor Neurons Kit includes cryopreserved motor neurons as well as neuronal medium and supplements. Innervation of muscle fibers by spinal motor neurons is essential for controlling muscle contraction and ultimately coordinated movement. Neurodegenerative diseases, such as ALS (Amyotrophic Lateral Sclerosis‎) and SMA (Spinal Muscular Atrophy), are a result of the progressive degeneration of motor neurons that leads to an uncoupling of this process. In order to provide researchers with a model system for understanding basic motor neuron biology and to develop treatments for these diseases, CDI offers iCell® Motor Neurons. iCell® Motor Neurons are a highly pure population of human spinal motor neurons derived from induced pluripotent stem (iPS) cells with the following features:

• Fully differentiated, ≥ 87% (β-III tubulin) pure population of primarily cholinergic human neurons (≥ 80% Isl1/2 at 14 days in vitro)
• Display typical neuronal morphology with branching neurites and remain viable for an extended culture period (≥ 14 days)
• Express markers characteristic of motor neurons
• Available in commercial quantities
• Easy to use: Simply thaw and plate

These cells provide a reliable source of human neurons suitable for use within:

• Basic and translational research: Studying neurodegenerative diseases like ALS & SMA, myelination/demyelination, and neurogenesis
• Drug discovery: For diseases such as ALS and SMA
• Bioengineering: Development of neuromuscular junction models
• Applied markets: BoNT testing
• Toxicology and safety pharma: For testing chemical warfare agents, effects of chemical pesticides, etc.

Certain products are only available in select territories. Please contact your local Sales Representative or Product & Scientific Support at techsupport@stemcell.com for further information.
Components:
iCell® Motor Neurons Kit, 01279, 1 x 10^6 cells (Catalog #R1051)
          iCell® Motor Neurons, 01279, 1 x 10^6 cells
          iCell® Neural Base Medium 1, 100 mL
          iCell® Neural Supplement A, 2 mL
          iCell® Nervous System Supplement, 1 mL  
 
iCell® Motor Neurons Kit, 01279, 3 x 10^6 cells (Catalog #R1049)
          iCell® Motor Neurons, 01279, 3 x 10^6 cells
          iCell® Neural Base Medium 1, 100 mL
          iCell® Neural Supplement A, 2 mL
          iCell® Nervous System Supplement, 1 mL
Subtype:
Frozen
Cell Type:
Neural Cells, PSC-Derived
Species:
Human
Cell and Tissue Source:
Pluripotent Stem Cells
Brand:
iCell
Donor Status:
Normal

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.