iCell® Hepatocytes 2.0 Kit, 01279

Hepatocytes derived from human iPS cells, frozen

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From: 595 USD

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Hepatocytes derived from human iPS cells, frozen
From: 595 USD

Overview

Well-characterized and readily available sources of human hepatocytes are required to advance new metabolic and infectious disease therapies, reduce the incidence of drug-induced liver injury, and accelerate the development of novel approaches to liver regeneration and transplantation.

iCell® Hepatocytes 2.0 overcome the functionality, reproducibility, and availability limitations of existing primary cell and tumor-derived cell models by providing the following:

• Relevant hepatic functionality and phenotypic stability
• Expression of clinical targets relevant for liver and metabolic disease
• Compatibility with a wide range of 3D and microphysiological systems
• Quality-controlled manufacturing and batch reproducibility
• Ready supply in a cryopreserved format

iCell® Hepatocytes 2.0 are being rapidly adopted for use in a wide range of applications:

• Diabetes research and drug discovery: Functional insulin and glucose regulation pathways and a flexible product format enable high-throughput screening for novel drug candidates
• Infectious disease studies: Native human biology and long-term phenotypic stability support hepatitis viral replication including growth of clinically relevant genotypes
• Hepatotoxicity assessment: Known genetic background and proven ability to detect metabolism-dependent and immune-mediated hepatotoxicity provide confidence in safety testing without the need for time-consuming and costly lot testing
• Liver tissue engineering: Compatibility with bioengineered scaffold engraftment, organ recellularization, and 3D printing enable new clinical and regenerative medicine strategies
• 3D spheroid culture: iCell® Hepatocytes form stable, highly uniform spheroids in low-attachment plates under a protocol developed at CDI enabling more in vivo-like three dimensional culture and applications
Components:
iCell® Hepatocytes 2.0 Kit, 01279, 3 x 10^6 cells (Catalog #R1104)
          iCell® Hepatocytes 2.0, 01279, 3 x 10^6 cells
          iCell® Hepatocytes 2.0 Medium Supplement, 2 x 3 mL
 
iCell® Hepatocytes 2.0 Kit, 01279, 1 x 10^7 cells (Catalog #R1025)
          iCell® Hepatocytes 2.0, 01279, 1x10^7 cells
          iCell® Hepatocytes 2.0 Medium Supplement, 2 x 3 mL
Subtype:
Frozen
Cell Type:
Hepatic Cells, PSC-Derived
Species:
Human
Cell and Tissue Source:
Pluripotent Stem Cells
Brand:
iCell
Donor Status:
Normal

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.