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The SARS-CoV-2 (NS6) Peptide Pool is a lyophilized mixture of 13 peptides from non-structural protein 6 (NS6) of SARS-CoV-2. SARS-CoV NS6 has been shown to localize in the endoplasmic reticulum/Golgi membrane of the host cell and disrupt nuclear import complex formation. This leads to the loss of STAT1 transport into the nucleus and inactivation of STAT1-activated genes that are required for antiviral effects. The sequence similarity of NS6 from the two coronaviruses suggests NS6 plays a similar role in SARS-CoV-2. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 - 61 on NS6.
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Serum-free and xeno-free medium for the expansion of human T cells
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SARS-CoV-2 (NS6) Peptide Pool
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
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