This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Data and Publications
(A) The biological activity of Human Recombinant Noggin was tested by its ability to inhibit BMP-4 induced alkaline phosphatase
production of ATDC-5 cells. Inhibitition of BMP-4 induced alkaline phosphatase production was measured using a fluorometric assay
method. The EC50 is defined as the effective concentration of the growth factor at which inhibition of alkaline phosphatase production is
at 50% of maximum. The EC50 in the above example is 1.9 ng/mL.
(B) 2 μg of Human Recombinant Noggin was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant Noggin has a predicted molecular mass of 30 kDa.