Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Neurotoxic peptide fragment

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Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Neurotoxic peptide fragment

From: 603 USD

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0.5 mg

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Neurotoxic peptide fragment

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Overview

Human Amyloid-β (1-42) Peptide is a neurotoxic peptide fragment that can oligomerize to form amyloid plaques, thus contributing to the onset of Alzheimer's disease (Paradis et al.; Teplow; Wolfe). These neurotoxic peptide fragments also modulate the expression of Bcl-2 and Bax in human neurons (Paradis et al.).

NOTE: Human Amyloid-β (1-42) Peptide oligomers and fibrils are considered neurotoxic. Please contact your workplace safety committee for guidance before planning any work using Human Amyloid-β (1-42) Peptide.

DISEASE MODELING
· Induces neuronal death in human neurons in vitro and in vivo (Paradis et al.).
· Increases production of TNF-α in rat astrocytes (Hughes et al.).

Aβ (1-42); Aβ42

Neurons

Disease Modeling, Neuroscience

≥ 95 %

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type

Product Name

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Lot #

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Document Type

Product Information Sheet

Product Name

Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Catalog #

100-0899

Lot #

All

Language

English

Document Type

Safety Data Sheet

Product Name

Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Catalog #

100-0899

Lot #

All

Language

English

Resources and Publications

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Quality Statement:

PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.

Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Neurotoxic peptide fragment

Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Neurotoxic peptide fragment

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Overview

Protocols and Documentation

Resources and Publications

Educational Materials (3)

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