TMRE (Perchlorate)

Cell-permeant, cationic fluorescent dye used to measure mitochondrial membrane potential

TMRE (Perchlorate)

Cell-permeant, cationic fluorescent dye used to measure mitochondrial membrane potential

From: 189 USD
Catalog #
100-0992_C
Cell-permeant, cationic fluorescent dye used to measure mitochondrial membrane potential

Overview

Detect changes in mitochondrial membrane potential with TMRE (Perchlorate) dye. TMRE uses a quick and simple staining protocol that is well suited for high-throughput screening and is compatible with flow cytometry.

Features:
• Excitation wavelength: 552 nm
• Emission wavelength: 574 nm
• Retention dependent on mitochondrial inner membrane potential
• Verified for use with flow cytometry

TMRE is a cell-permeant, cationic compound that emits a fluorescent red-orange signal. It readily accumulates in the mitochondria with high membrane potential, whereas depolarized mitochondria fail to retain the dye.

TMRE has a sufficient retention time that is optimal for cell sorting for further purification and characterization (Barteneva et al. J Histochem Cytochem, 2014). TMRE does not inhibit the mitochondrial function, and can be used in the identification of apoptotic cells (Barteneva et al., 2014).
Application
Flow Cytometry
CAS Number
115532-52-0

Scientific Resources

Product Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0992
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0992
Lot #
All
Language
English

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Data and Publications

Figure 1. TMRE (Perchlorate) Is Not Retained in Apoptotic Cells

Flow cytometry analysis of Jurkat cells labeled with TMRE after incubation in the presence or absence of staurosporine, an inducer of apoptosis.

Contact STEMCELL Technologies

Our Customer Service, Sales, and Product and Scientific Support departments in North America are available between 6 am and 5 pm Pacific Time (9 am and 8 pm Eastern Time). One of our representatives will be happy to help you by telephone or email. Please complete the form to contact us by email. A representative will get back to you shortly.
  •  

StemCell Technologies Inc. and affiliates ("STEMCELL Technologies") does not share your email address with third parties. StemCell Technologies Inc. will use your email address to confirm your identity and send you newsletters, transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.