Anti-Rat CD90 Antibody, Clone OX-7

Mouse monoclonal IgG1 antibody against mouse, rat, guinea pig CD90/CD90.1
From: 83 USD

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Mouse monoclonal IgG1 antibody against mouse, rat, guinea pig CD90/CD90.1
From: 83 USD

Overview

The OX-7 antibody reacts with rat CD90 (Thy-1) and mouse The OX-7 antibody reacts with rat CD90 (Thy-1) and mouse CD90.1 (Thy-1.1), the latter being an allelic form of CD90 expressed by mouse strains AKR/J, PL, and FVB/N. The OX-7 antibody does not react with CD90.2, which is expressed by many mouse strains, including CBA and BALB/c. CD90 is a GPI-linked membrane glycoprotein and member of the immunoglobulin superfamily. The 25 kDa core protein is N-glycosylated at three sites, giving rise to molecules with a range of molecular masses (25 - 37 kDa). In the rat, CD90 is expressed by several cell types, including hematopoietic stem cells, immature B cells, thymocytes and neurons. In mouse strains expressing CD90.1, it is found on early-stage hematopoietic cells in the bone marrow, thymocytes, and circulating mature T cells. The OX-7 antibody has been reported to induce leukocyte activation, glomerular nephritis, apoptosis in glomerular mesangial cells, and vascular permeability.

This antibody clone has been verified for purity assessments of cells isolated from compatible mouse strains with EasySep™ kits, including EasySep™ Mouse T Cell Isolation Kit (Catalog #19851).
Subtype:
Primary Antibodies
Target Antigen:
CD90/CD90.1
Alternative Names:
Thy-1, Thy-1.1
Reactive Species:
Guinea Pig; Mouse; Rabbit; Rat
Conjugation:
Alexa Fluor 488; APC; Biotin; FITC; PE; Unconjugated
Host Species:
Mouse
Cell Type:
T Cells
Application:
Flow Cytometry; Functional Assay; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting
Area of Interest:
Immunology
Clone:
OX-7
Gene ID:
21838/24832
Isotype:
IgG1, kappa

Scientific Resources

Educational Materials

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Data and Publications

Data

Data for Alexa Fluor® 488-Conjugated

Figure 1. Data for Alexa Fluor® 488-Conjugated

(A) Flow cytometry analysis of Sprague-Dawley rat brain cells labeled with Anti-Rat CD90 Antibody, Clone OX-7, Alexa Fluor® 488 (filled histogram) or a mouse IgG1, kappa Alexa Fluor® 488 isotype control antibody (solid line histogram).
(B) Flow cytometry analysis of Sprague-Dawley rat thymocytes labeled with Anti-Rat CD90 Antibody, Clone OX-7, Alexa Fluor® 488 (filled histogram) or a mouse IgG1, kappa Alexa Fluor® 488 isotype control antibody (solid line histogram).

Data for PE-Conjugated

Figure 2. Data for PE-Conjugated

(A) Flow cytometry analysis of Sprague-Dawley rat brain cells labeled with Anti-Rat CD90 Antibody, Clone OX-7, PE (filled histogram) or a mouse IgG1, kappa PE isotype control antibody (solid line histogram).
(B) Flow cytometry analysis of Sprague-Dawley rat thymocytes labeled with Anti-Rat CD90 Antibody, Clone OX-7, PE (filled histogram) or a mouse IgG1, kappa PE isotype control antibody (solid line histogram).

Data for Unconjugated

Figure 3. Data for Unconjugated

(A) Flow cytometry analysis of Sprague-Dawley rat brain cells labeled with Anti-Rat CD90 Antibody, Clone OX-7, followed by a rat anti-mouse IgG1 antibody, PE (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21 (Catalog #60070), followed by a rat anti-mouse IgG1 antibody, PE (solid line histogram). (B) Flow cytometry analysis of Sprague-Dawley rat thymocytes labeled with Anti-Rat CD90 Antibody, Clone OX-7, followed by a rat anti-mouse IgG1 antibody, PE (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, followed by a rat anti-mouse IgG1 antibody, PE (solid line histogram).

Data for APC-Conjugated

Figure 4. Data for APC-Conjugated

(A) Flow cytometry analysis of Sprague-Dawley rat brain cells labeled with Anti-Rat CD90 Antibody, Clone OX-7, APC (filled histogram) or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, APC (Catalog #60070AZ) (solid line histogram). (B) Flow cytometry analysis of Sprague-Dawley rat thymocytes labeled with Anti-Rat CD90 Antibody, Clone OX-7, APC (filled histogram) or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, APC (solid line histogram).

Data for Biotin-Conjugated

Figure 5. Data for Biotin-Conjugated

(A) Flow cytometry analysis of Sprague-Dawley rat brain cells labeled with Anti-Rat CD90 Antibody, Clone OX-7, Biotin, followed by streptavidin (SAV) APC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, Biotin (Catalog #60070BT), followed by SAV APC (solid line histogram). (B) Flow cytometry analysis of Sprague-Dawley rat thymocytes labeled with Anti-Rat CD90 Antibody, Clone OX-7, Biotin, followed by SAV APC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, Biotin, followed by SAV APC (solid line histogram).

Data for FITC-Conjugated

Figure 6. Data for FITC-Conjugated

(A) Flow cytometry analysis of Sprague-Dawley rat brain cells labeled with Anti-Rat CD90 Antibody, Clone OX-7, FITC (filled histogram) or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, FITC (Catalog #60070FI) (solid line histogram). (B) Flow cytometry analysis of Sprague-Dawley rat thymocytes labeled with Anti-Rat CD90 Antibody, Clone OX-7, FITC (filled histogram) or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, FITC (solid line histogram).

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.